Systemic Lupus Erythematosus. Case presentation.

Abstract

Systemic Erythematosus lupus is the paradigm of de syndrome or autoimmune systemic disease etiology is far from clear, although ºthe understanding of disease pathogenesis progresses as the deepest  of the immune system functioning. It is more common in women than men (10:1) and usually occurs between late adolescence and 50 years old. It is more frequent and severe in some ethnic groups, particularly Afro - Americans and Hispanics. The chronic nature, with activation episodes or outbreaks, the presence of numerous auto antibodies in serum, the great clinical variability and responsive immunosuppressive therapy demonstrates its autoimmune nature. Undoubtedly, the result of our ignorance, the current diagnostic and therapeutic approach can be considered rudimentary and susceptible to substantial changes in the near future. A 38 years old masculine patient is presented without history of disease, referring  for the last  3 months the following symptoms: asthenia, adynamia, loss of appetite, 10 kg weight loss, joint pain, edema in his legs swelling, and presence of fever during the last week from 38.5°C to 39.0°C.